CDK4-IN-1
| Code | Size | Price |
|---|
| TAR-T2082-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50=5.265 uM) respectively.
CAS:
1256963-02-6
Formula:
C22H29ClN8
Molecular Weight:
440.98
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
CC(C)c1[nH]nc(Cl)c1-c1ccnc(Nc2ccc(cn2)N2CCC(CC2)N(C)C)n1
Target:
CDK
References
1. Cho YS, et al. J Med Chem. 2010 Nov 25;53(22):7938-57.