TargetMol

Ancitabine

Product Code:
 
TAR-T21161
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21161-5mg5mg£850.00
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TAR-T21161-50mg50mg£1,661.00
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Quantity:
TAR-T21161-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ancitabine, a congener of cyterabine, is metabolized to cytarabine, thereby maintains a more constant antineoplastic action.
CAS:
31698-14-3
Formula:
C9H11N3O4
Molecular Weight:
225.204
Purity:
0.98
SMILES:
[H][C@@]12Oc3nc(=N)ccn3[C@]1([H])O[C@H](CO)[C@H]2O

References

1. Kirsch LE, Notari RE. Pharmacokinetic prodrug modeling: in vitro and in vivo kinetics and mechanisms of ancitabine bioconversion to cytarabine. J Pharm Sci. 1984 Jun;73(6):728-32. PubMed PMID: 6204036. 2. Kirsch LE, Notari RE. Aqueous conversion kinetics and mechanisms of ancitabine, a prodrug of the antileukemic agent cytarabine. J Pharm Sci. 1984 Jul;73(7):896-902. PubMed PMID: 6206222. 3. Webb TR, Mitsuya H, Broder S. 1-(2,3-Anhydro-beta-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus. J Med Chem. 1988 Jul;31(7):1475-9. PubMed PMID: 2455053. 4. Nakamura K, Eizuru Y, Kumura K, Minamishima Y. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. J Med Virol. 1990 Jun;31(2):141-7. PubMed PMID: 1696958.