4-(Trifluoromethyl)phenylboronic acid
| Code | Size | Price |
|---|
| TAR-T21356-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
4-(Trifluoromethyl)benzeneboronic acid is used to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones.
CAS:
128796-39-4
Formula:
C7H6BF3O2
Molecular Weight:
189.93
Purity:
0.98
SMILES:
OB(O)c1ccc(cc1)C(F)(F)F
References
1. Cao KS, Bian HX, Zheng WH. Mild arylboronic acid catalyzed selective [4 + 3] cycloadditions: access to cyclohepta[b]benzofurans and cyclohepta[b]indoles. Org Biomol Chem. 2015 Jun 21;13(23):6449-52. doi: 10.1039/c5ob00653h. Epub 2015 May 14. PubMed PMID: 25971529.
2. Christinat N, Scopelliti R, Severin K. Boron-based rotaxanes by multicomponent self-assembly. Chem Commun (Camb). 2008 Aug 21;(31):3660-2. doi: 10.1039/b805437a. Epub 2008 Jun 11. PubMed PMID: 18665291.
3. Maki T, Ishihara K, Yamamoto H. 4,5,6,7-Tetrachlorobenzo[d][1,3,2]dioxaborol- 2-ol as an effective catalyst for the amide condensation of sterically demanding carboxylic acids. Org Lett. 2006 Mar 30;8(7):1431-4. PubMed PMID: 16562909.
4. Westmark PR, Smith BD. Boronic acids facilitate the transport of ribonucleosides through lipid bilayers. J Pharm Sci. 1996 Mar;85(3):266-9. PubMed PMID: 8699326.