Butenafine
| Code | Size | Price |
|---|
| TAR-T21365-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Butenafine hydrochloride is a hydrochloride of butenafine, which inhibits squalene epoxidase to inhibit the synthesis of ergosterol, leading to the increased permeability of the cell membranes, allowing their contents to leak out.
CAS:
101828-21-1
Formula:
C23H27N
Molecular Weight:
317.476
Purity:
0.98
SMILES:
CN(Cc1ccc(cc1)C(C)(C)C)Cc1cccc2ccccc12
References
1. Fu MC, Shang R, Cheng WM, Fu Y. Boron-Catalyzed N-Alkylation of Amines using Carboxylic Acids. Angew Chem Int Ed Engl. 2015 Jul 27;54(31):9042-6. doi: 10.1002/anie.201503879. Epub 2015 Jul 6. PubMed PMID: 26150397.
2. Pillai AB, Nair JV, Gupta NK, Gupta S. Microemulsion-loaded hydrogel formulation of butenafine hydrochloride for improved topical delivery. Arch Dermatol Res. 2015 Sep;307(7):625-33. doi: 10.1007/s00403-015-1573-z. Epub 2015 May 26. PubMed PMID: 26006164.
3. Ely JW, Rosenfeld S, Seabury Stone M. Diagnosis and management of tinea infections. Am Fam Physician. 2014 Nov 15;90(10):702-10. PubMed PMID: 25403034.