Cefotetan disodium
| Code | Size | Price |
|---|
| TAR-T21400-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cefotetan Sodium, a second-generation cephalosporin, cephamycin antibiotic, is active against a wide range of both aerobic and anaerobic gram-negative and gram-positive bacteria. Cefotetan disrupts the cell wall synthesis by binding to penicillin-binding proteins.
CAS:
74356-00-6
Formula:
C17H15N7Na2O8S4
Molecular Weight:
619.57
Purity:
0.98
SMILES:
[Na+].[Na+].COC1(NC(=O)C2SC(S2)=C(C(N)=O)C([O-])=O)C2SCC(CSc3nnnn3C)=C(N2C1=O)C([O-])=O
References
1. Nam YH, Hwang EK, Ban GY, Jin HJ, Yoo HS, Shin YS, Ye YM, Nahm DH, Park HS, Lee SK. Immunologic evaluation of patients with cefotetan-induced anaphylaxis. Allergy Asthma Immunol Res. 2015 May;7(3):301-3. doi: 10.4168/aair.2015.7.3.301. PubMed PMID: 25749763; PubMed Central PMCID: PMC4397372.
2. Liu Y, Huang J, Liu J, Ma L, Lv Y, Shi S. A simple and sensitive liquid chromatographic technique for the determination of cefotetan disodium in human plasma and its application in a pharmacokinetic study. J Huazhong Univ Sci Technolog Med Sci. 2012 Oct;32(5):779-84. doi: 10.1007/s11596-012-1034-2. PubMed PMID: 23073813.
3. Su MX, Liu MH, Di B, Huang LL, Jiang Y, Ma PC, Hang TJ. Pharmacokinetic differences between the epimers of cefotetan disodium after single intravenous injection in healthy Chinese volunteers. Eur J Drug Metab Pharmacokinet. 2011 Dec;36(4):223-8. doi: 10.1007/s13318-011-0064-7. PubMed PMID: 21915733.
4. Shi S, Liu Y, Li Z, Zheng H, Lv Y, Chen H. Pharmacokinetics and tolerability of intravenous cefotetan disodium for injection in healthy Chinese volunteers: A randomized, open-label, single- and multiple-dose study. Clin Ther. 2010 Sep;32(10):1832-41. doi: 10.1016/j.clinthera.2010.09.015. PubMed PMID: 21194607.