NCC-149
Code | Size | Price |
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TAR-T21421-5mg | 5mg | £277.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T21421-50mg | 50mg | £1,026.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T21421-100mg | 100mg | £1,532.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
NCC-149 is a HDAC8 inhibitor.
CAS:
1316652-41-1
Formula:
C16H14N4O2S
Molecular Weight:
326.37
Purity:
0.98
SMILES:
ONC(=O)c1cccc(c1)-c1cn(CSc2ccccc2)nn1
References
1. Identification of a Novel Aminotetralin Class of HDAC6 and HDAC8 Selective Inhibitors. By Tang, Guozhi; Wong, Jason C.; Zhang, Weixing; Wang, Zhanguo; Zhang, Nan; Peng, Zhenghong; Zhang, Zhenshan; Rong, Yiping; Li, Shijie; Zhang, Meifang; et al. From Journal of Medicinal Chemistry (2014), 57(19), 8026-8034.
2. Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8-?Selective Inhibitors. By Suzuki, Takayoshi; Muto, Nobusuke; Bando, Masashige; Itoh, Yukihiro; Masaki, Ayako; Ri, Masaki; Ota, Yosuke; Nakagawa, Hidehiko; Iida, Shinsuke; Shirahige, Katsuhiko; et al. From ChemMedChem (2014), 9(3), 657-664.
3. Rapid Discovery of Highly Potent and Selective Inhibitors of Histone Deacetylase 8 Using Click Chemistry to Generate Candidate Libraries. Suzuki, Takayoshi; Ota, Yosuke; Ri, Masaki; Bando, Masashige; Gotoh, Aogu; Itoh, Yukihiro; Tsumoto, Hiroki; Tatum, Prima R.; Mizukami, Tamio; Nakagawa, Hidehiko; et al. From Journal of Medicinal Chemistry (2012), 55(22), 9562-9575.
4. Preparation of hydroxamic acid derivatives as HDAC8 inhibitors. By Miyata, Naoki; Suzuki, Takayoshi; Ota, Yosuke; Ueda, Ryuzo; Iida, Shinsuke; Ri, Masaki. From PCT Int. Appl. (2011), WO 2011089995 A1 20110728.