Physostigmine
| Code | Size | Price |
|---|
| TAR-T21438-5mg | 5mg | £309.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Physostigmine is a potent and reversible inhibitor of cholinesterase. It is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE).
CAS:
57-47-6
Formula:
C15H21N3O2
Molecular Weight:
275.352
Purity:
0.98
SMILES:
CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1
References
1. Glatstein MM, Alabdulrazzaq F, Garcia-Bournissen F, Scolnik D. Use of physostigmine for hallucinogenic plant poisoning in a teenager: case report and review of the literature. Am J Ther. 2012 Sep;19(5):384-8. doi: 10.1097/MJT.0b013e3181f0cbb4. Review. PubMed PMID: 20861718.
2. Frascogna N. Physostigmine: is there a role for this antidote in pediatric poisonings? Curr Opin Pediatr. 2007 Apr;19(2):201-5. Review. PubMed PMID: 17496766.
3. Allen L, Alsalim W. Best evidence topic report. Gammahydroxybutyrate overdose and physostigmine. Emerg Med J. 2006 Apr;23(4):300-1. Review. PubMed PMID: 16549578; PubMed Central PMCID: PMC2579509.
4. Traub SJ, Nelson LS, Hoffman RS. Physostigmine as a treatment for gamma-hydroxybutyrate toxicity: a review. J Toxicol Clin Toxicol. 2002;40(6):781-7. Review. PubMed PMID: 12475191.