Diphenylcyclopropenone

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TargetMol
Product Code: TAR-T21444
Supplier: TargetMol
CodeSizePrice
TAR-T21444-500mg500mg£102.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T21444-1mL1 mL * 10 mM (in DMSO)£105.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Diphencyprone is a topical drug used to treat alopecia areata, alopecia totalis, and refractory warts. Diphencyprone acts as a local stimulator that triggers an immune response against the action of autoreactive cells.
CAS:
886-38-4
Formula:
C15H10O
Molecular Weight:
206.244
Purity:
0.999
SMILES:
O=c1c(c1-c1ccccc1)-c1ccccc1

References

1. Moncrieff M, Fadhil M, Garioch J. Topical diphencyprone for the treatment of locoregional intralymphatic melanoma metastases (LIMMs) of the skin. The 5-Year Norwich experience. Br J Dermatol. 2015 Nov 24. 2. Bulock KG, Cardia JP, Pavco PA, Levis WR. Diphencyprone Treatment of Alopecia Areata: Postulated Mechanism of Action and Prospects for Therapeutic Synergy with RNA Interference. J Investig Dermatol Symp Proc. 2015 Nov;17(2):16-8. 3. Moncrieff M, Fadhil M, Garioch J. Topical diphencyprone for the treatment of locoregional intralymphatic melanoma metastases (LIMMs) of the skin. The 5-Year Norwich experience. Br J Dermatol. 2015 Nov 24. doi: 10.1111/bjd.14314. [Epub ahead of print] PubMed PMID: 26598951. 4. Lamb RC, Young D, Holmes S. Retrospective review of diphencyprone in the treatment of alopecia areata. Clin Exp Dermatol. 2015 Dec 1.