MeBIO

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TargetMol
Product Code: TAR-T21966
Supplier: TargetMol
CodeSizePrice
TAR-T21966-1mg1mg£97.00
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TAR-T21966-5mg5mg£125.00
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TAR-T21966-1mL1 mL * 10 mM (in DMSO)£133.00
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TAR-T21966-10mg10mg£166.00
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TAR-T21966-25mg25mg£257.00
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TAR-T21966-50mg50mg£370.00
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TAR-T21966-100mg100mg£510.00
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TAR-T21966-500mg500mg£1,026.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.
CAS:
667463-95-8
Formula:
C17H12BrN3O2
Molecular Weight:
370.2
Pathway:
Stem Cells; PI3K/Akt/mTOR signaling; Cell Cycle/Checkpoint; Immunology/Inflammation
Purity:
0.9884
SMILES:
CN(c(cc(cc1)Br)c1/C1=C2/Nc(cccc3)c3/C2=NO)C1=O
Target:
GSK-3; Aryl Hydrocarbon Receptor; CDK

References

1. Meijer L, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol. 2003 Dec;10(12):1255-66.