GW 4064

TargetMol
Product Code: TAR-T2233
Supplier: TargetMol
CodeSizePrice
TAR-T2233-5mg5mg£107.00
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Quantity:
TAR-T2233-1mL1 mL * 10 mM (in DMSO)£116.00
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Quantity:
TAR-T2233-10mg10mg£132.00
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Quantity:
TAR-T2233-25mg25mg£185.00
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Quantity:
TAR-T2233-50mg50mg£269.00
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Quantity:
TAR-T2233-100mg100mg£430.00
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TAR-T2233-200mg200mg£611.00
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TAR-T2233-500mg500mg£922.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).
CAS:
278779-30-9
Formula:
C28H22Cl3NO4
Molecular Weight:
542.84
Pathway:
Autophagy; Metabolism
Purity:
0.9994
SMILES:
CC(C)c1onc(c1COc1ccc(C=Cc2cccc(c2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl
Target:
FXR; Autophagy

References

1. Akwabi-Ameyaw A et al., Bioorg Med Chem Lett, 2008, 18(15), 4339-4343. 2. Maloney PR, et al., J Med Chem, 2000, 43(16), 2971-2974.