AS-605240

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TargetMol
Product Code: TAR-T2248
Supplier: TargetMol
CodeSizePrice
TAR-T2248-5mg5mg£95.00
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Quantity:
TAR-T2248-1mL1 mL * 10 mM (in DMSO)£98.00
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Quantity:
TAR-T2248-10mg10mg£112.00
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Quantity:
TAR-T2248-25mg25mg£157.00
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Quantity:
TAR-T2248-50mg50mg£238.00
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Quantity:
TAR-T2248-100mg100mg£309.00
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Quantity:
TAR-T2248-200mg200mg£404.00
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Quantity:
TAR-T2248-500mg500mg£624.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).
CAS:
648450-29-7
Formula:
C12H7N3O2S
Molecular Weight:
257.27
Pathway:
Autophagy; PI3K/Akt/mTOR signaling
Purity:
0.9991
SMILES:
O=C1NC(=O)C(S1)=Cc1ccc2nccnc2c1
Target:
PI3K; Autophagy

References

1. Camps M, et al. Nat Med, 2005, 11(9), 936-943. 2. Kim JI, et al. Nat Neurosci, 2011, 14(11), 1447-1454. 3. Kobayashi N, et al. Proc Natl Acad Sci U S A, 2011, 108(14), 5753-5758.