SC79
Code | Size | Price |
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TAR-T2274-5mg | 5mg | £112.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2274-1mL | 1 mL * 10 mM (in DMSO) | £116.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2274-10mg | 10mg | £140.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2274-25mg | 25mg | £185.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2274-50mg | 50mg | £229.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2274-100mg | 100mg | £334.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2274-200mg | 200mg | £495.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
SC79, a selective Akt activator, may be used to enhance Akt activity in various pathological and physiological conditions.
CAS:
305834-79-1
Formula:
C17H17ClN2O5
Molecular Weight:
364.78
Pathway:
PI3K/Akt/mTOR signaling; Cytoskeletal Signaling
Purity:
0.98
SMILES:
CCOC(=O)C(C#N)C1C(C(=O)OCC)=C(N)Oc2ccc(Cl)cc12
Target:
Akt
References
1. Jo H, et al. Proc Natl Acad Sci U S A. 2012, 109(26), 10581-10586.
2. So EY, et al. BMC Cancer. 2014, 14, 548.
3. Wang X, Zhu P, Xu S, et al. Antimony,a novel nerve poison, triggers neuronal autophagic death via reactive oxygen species-mediated inhibition of the protein kinase B/mammalian target of rapamycin pathway[J]. The International Journal of Biochemistry & Cell Biology. 2019: 105561.
4. Shi W, Tang Y, Zhi Y, et al. Akt inhibition-dependent downregulation of the Wnt/?-Catenin Signaling pathway contributes to antimony-induced neurotoxicity. Science of the Total Environment. 2020, 737: 140252.