BIIB021

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TargetMol
Product Code: TAR-T2286
Supplier: TargetMol
CodeSizePrice
TAR-T2286-5mg5mg£109.00
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TAR-T2286-1mL1 mL * 10 mM (in DMSO)£112.00
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Quantity:
TAR-T2286-10mg10mg£125.00
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Quantity:
TAR-T2286-25mg25mg£157.00
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Quantity:
TAR-T2286-50mg50mg£209.00
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Quantity:
TAR-T2286-100mg100mg£282.00
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TAR-T2286-200mg200mg£432.00
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TAR-T2286-500mg500mg£666.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
BIIB021 is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).
CAS:
848695-25-0
Formula:
C14H15ClN6O
Molecular Weight:
318.77
Pathway:
Autophagy; Cytoskeletal Signaling; Metabolism
Purity:
0.9838
SMILES:
COc1c(C)cnc(Cn2cnc3c(Cl)nc(N)nc23)c1C
Target:
HSP; Autophagy

References

1. Lundgren K, et al. Mol Cancer Ther, 2009, 8(4), 921-929. 2. B?ll B, et al. Clin Cancer Res, 2009, 15(16), 5108-5116. 3. Yin X, et al. Int J Cancer, 2010, 126(5), 1216-1225. 4. Zhang H, et al. Int J Cancer, 2010, 126(5), 1226-1234.