BMS-833923

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TargetMol
Product Code: TAR-T2299
Supplier: TargetMol
CodeSizePrice
TAR-T2299-5mg5mg£107.00
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Quantity:
TAR-T2299-1mL1 mL * 10 mM (in DMSO)£114.00
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Quantity:
TAR-T2299-10mg10mg£130.00
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Quantity:
TAR-T2299-25mg25mg£174.00
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Quantity:
TAR-T2299-50mg50mg£238.00
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Quantity:
TAR-T2299-100mg100mg£373.00
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Quantity:
TAR-T2299-200mg200mg£515.00
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TAR-T2299-500mg500mg£776.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
BMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
CAS:
1059734-66-5
Formula:
C30H27N5O
Molecular Weight:
473.58
Pathway:
Apoptosis; Stem Cells; GPCR/G Protein
Purity:
0.9974
SMILES:
CNCc1ccc(C)c(NC(=O)c2ccc(Nc3nc(-c4ccccc4)c4ccccc4n3)cc2)c1
Target:
Apoptosis; Hedgehog/Smoothened; Smo

References

1. Tang JY, et al. Semin Cutan Med Surg. 2011, 30(4 Suppl), S14-18. 2. Zaidi AH, et al. Cancer Invest. 2013, 31(7), 480-489. 3. Wilkinson SE, et al. Prostate. 2013, 73(16), 1810-1823.