PF-431396

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TargetMol
Product Code: TAR-T2314
Supplier: TargetMol
CodeSizePrice
TAR-T2314-5mg5mg£111.00
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Quantity:
TAR-T2314-1mL1 mL * 10 mM (in DMSO)£118.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2314-10mg10mg£130.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2314-25mg25mg£189.00
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Quantity:
TAR-T2314-50mg50mg£280.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2314-100mg100mg£430.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2314-200mg200mg£600.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
CAS:
717906-29-1
Formula:
C22H21F3N6O3S
Molecular Weight:
506.5
Pathway:
Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Purity:
0.9982
SMILES:
CN(c1ccccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
Target:
FAK; PYK2

References

1. Han S, et al. J Biol Chem. 2009, 284(19), 13193-13201. 2. Tse KW, et al. J Biol Chem. 2009, 284(34), 22865-22877. 3. Gonz?lez-Fern?ndez L, et al. Biol Reprod. 2013, 88(6), 13