Pelitinib

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TargetMol
Product Code: TAR-T2327
Supplier: TargetMol
CodeSizePrice
TAR-T2327-5mg5mg£105.00
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TAR-T2327-1mL1 mL * 10 mM (in DMSO)£109.00
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Quantity:
TAR-T2327-10mg10mg£119.00
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TAR-T2327-25mg25mg£156.00
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Quantity:
TAR-T2327-50mg50mg£177.00
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TAR-T2327-100mg100mg£230.00
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TAR-T2327-500mg500mg£464.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Pelitinib (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).
CAS:
257933-82-7
Formula:
C24H23ClFN5O2
Molecular Weight:
467.93
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors; MAPK; JAK/STAT signaling
Purity:
0.9986
SMILES:
CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C
Target:
EGFR; Raf; MEK; Src

References

1. Torrance CJ, et al. Nat Med, 2000, 6(9), 1024-1028. 2. Nunes M, et al. Mol Cancer Ther, 2004, 3(1), 21-27. 3. Tyner JW, et al. J Clin Invest, 2006, 116(2), 309-321.