AMI-1

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TargetMol
Product Code: TAR-T2352
Supplier: TargetMol
CodeSizePrice
TAR-T2352-5mg5mg£105.00
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TAR-T2352-1mL1 mL * 10 mM (in DMSO)£112.00
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Quantity:
TAR-T2352-10mg10mg£122.00
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Quantity:
TAR-T2352-25mg25mg£173.00
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Quantity:
TAR-T2352-50mg50mg£222.00
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Quantity:
TAR-T2352-100mg100mg£309.00
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Quantity:
TAR-T2352-500mg500mg£647.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).
CAS:
20324-87-2
Formula:
C21H14N2Na2O9S2
Molecular Weight:
548.45
Pathway:
Chromatin/Epigenetic
Purity:
0.999
SMILES:
[Na+].[Na+].Oc1cc(cc2cc(NC(=O)Nc3ccc4c(O)cc(cc4c3)S([O-])(=O)=O)ccc12)S([O-])(=O)=O
Target:
Histone Methyltransferase

References

1. Cheng D, et al. J Biol Chem. 2004, 279(23), 23892-23899. 2. Skillman AG, et al. Bioorg Chem. 2002, 30(6), 443-458. 3. Sun Q, et al. J Immunol. 2015, 195(1), 298-306. 4. Lv L, et al. Endocrine. 2015,49(3), 669-682.