AF-710B
Code | Size | Price |
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TAR-T23649-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23649-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23649-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
AF710B is an enantiomer of AF710. AF-710B is also a sigma and M1 muscarinic receptors agonist.
CAS:
1235733-73-9
Formula:
C20H27N3OS
Molecular Weight:
357.52
Purity:
0.98
SMILES:
CC1SC2(CN1C(=O)CCc1c[nH]c3ccccc13)CCN(C)CC2
References
1. Hall H, Iulita MF, Gubert P, Flores Aguilar L, Ducatenzeiler A, Fisher A, Cuello AC. AF710B, an M1/sigma-1 receptor agonist with long-lasting disease-modifying properties in a transgenic rat model of Alzheimer's disease. Alzheimers Dement. 2017 Dec 29. pii: S1552-5260(17)33851-7. doi: 10.1016/j.jalz.2017.11.009. [Epub ahead of print] PubMed PMID: 29291374.
2. Fisher A, Bezprozvanny I, Wu L, Ryskamp DA, Bar-Ner N, Natan N, Brandeis R, Elkon H, Nahum V, Gershonov E, LaFerla FM, Medeiros R. AF710B, a Novel M1/?1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer?s Disease. Neurodegener Dis. 2016;16(1-2):95-110. PubMed PMID: 26606130; PubMed Central PMCID: PMC4803577.