AH-1058 HCl
Code | Size | Price |
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TAR-T23672-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23672-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23672-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
AH-1058 HCl is a lipophilic antiarrhythmic calcium channel blocker.
CAS:
228123-15-7
Formula:
C30H29ClN2O3
Molecular Weight:
501.02
Purity:
0.98
SMILES:
Cl.COc1cccc(C=CCN2CCC(CC2)=C2c3ccccc3C=Cc3ccccc23)c1[N+]([O-])=O
References
1. Dohmoto H, Takahara A, Uneyama H, Yoshimoto R. Cardiac Ca(2+) channel-blocking effects of the cyproheptadine derivative AH-1058 in isolated guinea pig cardiomyocytes. J Pharmacol Sci. 2003 Feb;91(2):163-6. PubMed PMID: 12686762.
2. Takahara A, Sugiyama A, Yoshimoto R, Hashimoto K. AH-1058: a novel cardioselective Ca2+ channel blocker. Cardiovasc Drug Rev. 2001 Winter;19(4):279-96. Review. PubMed PMID: 11830748.
3. Takahara A, Hirasawa A, Dohmoto H, Shoji M, Yoshimoto R, Sugiyama A, Hashimoto K. In vivo antiarrhythmic profile of AP-792 assessed in different canine arrhythmia models. Jpn J Pharmacol. 2001 Sep;87(1):21-6. PubMed PMID: 11676194.
4. Takahara A, Dohmoto H, Yoshimoto R, Sugiyama A, Hashimoto K. Utilization of telemetry system to assess the cardiovascular profile of AH-1058, a new cardioselective Ca2+ channel blocker, in conscious dogs. Jpn J Pharmacol. 2001 Mar;85(3):331-4. PubMed PMID: 11325028.