AKCI
Code | Size | Price |
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TAR-T23693-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23693-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23693-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.
CAS:
669750-88-3
Formula:
C19H27N7O
Molecular Weight:
369.473
Purity:
0.98
SMILES:
Cc1cccc2c(C)nc(=NC3=NCN(CCN4CCOCC4)CN3)[nH]c12
References
1. Patthy A, Moln?r T, Porrogi P, Naud? R, Gr?f L. Isolation and characterization of a protease inhibitor from Acacia karroo with a common combining loop and overlapping binding sites for chymotrypsin and trypsin. Arch Biochem Biophys. 2015 Jan 1;565:9-16. doi: 10.1016/j.abb.2014.11.001. Epub 2014 Nov 8. PubMed PMID: 25447841.
2. Ulu SM, Ahsen A, Akc? ?, Yaman F, Demir K, Yaman G, Y?ksel ?, Acart?rk G. The relationship between dipping-non-dipping arterial blood pressure pattern and frequency of restless leg syndrome with related factors. Anatol J Cardiol. 2015 Apr;15(4):284-8. doi: 10.5152/akd.2014.5381. Epub 2014 Apr 16. PubMed PMID: 25413225; PubMed Central PMCID: PMC5336836.
3. Han EH, Min JY, Yoo SA, Park SJ, Choe YJ, Yun HS, Lee ZW, Jin SW, Kim HG, Jeong HG, Kim HK, Kim ND, Chung YH. A small-molecule inhibitor targeting the AURKC-I?B? interaction decreases transformed growth of MDA-MB-231 breast cancer cells. Oncotarget. 2017 Jun 29;8(41):69691-69708. doi: 10.18632/oncotarget.18883. eCollection 2017 Sep 19. PubMed PMID: 29050234; PubMed Central PMCID: PMC5642509.