Amperozide HCl
| Code | Size | Price |
|---|
| TAR-T23733L-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Amperozide HCl is an antagonist of 5-HT2/D2. It inhibits nomifensine-induced hyperlocomotion and human FAAH.
CAS:
75529-73-6
Formula:
C23H29F2N3O
Molecular Weight:
401.5
Purity:
0.98
SMILES:
O=C(N1CCN(CCCC(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3)CC1)NCC
References
1. Nuss AB, Ejendal KF, Doyle TB, Meyer JM, Lang EG, Watts VJ, Hill CA. Dopamine receptor antagonists as new mode-of-action insecticide leads for control of Aedes and Culex mosquito vectors. PLoS Negl Trop Dis. 2015 Mar 20;9(3):e0003515. doi: 10.1371/journal.pntd.0003515. eCollection 2015 Mar. PubMed PMID: 25793586; PubMed Central PMCID: PMC4368516.
2. Vincent F, Nguyen MT, Emerling DE, Kelly MG, Duncton MA. Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6793-6. doi: 10.1016/j.bmcl.2009.09.086. Epub 2009 Sep 30. PubMed PMID: 19850474.
3. Chang PY, Chuang CH, Chen JC, Tung CS. Behavioral and biochemical effects of amperozide and serotonin agents on nigrostriatal and mesolimbic dopamine systems. Chin J Physiol. 2008 Apr 30;51(2):106-15. Erratum in: Chin J Physiol. 2008 Jun 30;51(3):196. PubMed PMID: 18666714.
4. McMillen BA, Shank JE, Jordan KB, Williams HL, Basile AS. Effect of DOV 102,677 on the volitional consumption of ethanol by Myers' high ethanol-preferring rat. Alcohol Clin Exp Res. 2007 Nov;31(11):1866-71. Epub 2007 Sep 26. PubMed PMID: 17908267.