WC-9

TargetMol
Product Code: TAR-T23767
Supplier: TargetMol
CodeSizePrice
TAR-T23767-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23767-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23767-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
WC-9 is a squalene synthase inhibitor. It acts by binding to TcSQS and HsSQS.
CAS:
205381-53-9
Formula:
C15H13NO2S
Molecular Weight:
271.33
Purity:
0.98
SMILES:
N#CSCCOc1ccc(Oc2ccccc2)cc1

References

1. Peltzer K, Pengpid S. The Association of Dietary Behaviors and Physical Activity Levels with General and Central Obesity among ASEAN University Students. AIMS Public Health. 2017 Jun 23;4(3):301-313. doi: 10.3934/publichealth.2017.3.301. eCollection 2017. PubMed PMID: 29546219; PubMed Central PMCID: PMC5690456. 2. Chao MN, Storey M, Li C, Rodr?guez MG, Di Salvo F, Szajnman SH, Moreno SNJ, Docampo R, Rodriguez JB. Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation. Bioorg Med Chem. 2017 Dec 15;25(24):6435-6449. doi: 10.1016/j.bmc.2017.10.016. Epub 2017 Oct 16. PubMed PMID: 29107437. 3. Chao MN, Li C, Storey M, Falcone BN, Szajnman SH, Bonesi SM, Docampo R, Moreno SN, Rodriguez JB. Activity of Fluorine-Containing Analogues of WC-9 and Structurally Related Analogues against Two Intracellular Parasites: Trypanosoma cruzi and Toxoplasma gondii. ChemMedChem. 2016 Dec 16;11(24):2690-2702. doi: 10.1002/cmdc.201600505. Epub 2016 Nov 25. PubMed PMID: 27886451; PubMed Central PMCID: PMC5200956. 4. Vadiveloo M, Sacks FM, Champagne CM, Bray GA, Mattei J. Greater Healthful Dietary Variety Is Associated with Greater 2-Year Changes in Weight and Adiposity in the Preventing Overweight Using Novel Dietary Strategies (POUNDS Lost) Trial. J Nutr. 2016 Aug;146(8):1552-9. doi: 10.3945/jn.115.224683. Epub 2016 Jun 29. PubMed PMID: 27358422; PubMed Central PMCID: PMC4958287.