Benzatropine

TargetMol
Product Code: TAR-T23781
Supplier: TargetMol
CodeSizePrice
TAR-T23781-5mg5mg£850.00
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Quantity:
TAR-T23781-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23781-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Benzatropine is a centrally active muscarinic antagonist. It also inhibits the uptake of dopamine. It has been used in the symptomatic treatment of Parkinson's Disease.
CAS:
86-13-5
Formula:
C21H25NO
Molecular Weight:
307.437
Purity:
0.98
SMILES:
CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccccc1

References

1. McIntyre IM, Mallett P, Burton CG, Morhaime J. Acute benztropine intoxication and fatality. J Forensic Sci. 2014 Nov;59(6):1675-8. doi: 10.1111/1556-4029.12489. Epub 2014 Apr 3. PubMed PMID: 24697166. 2. Hiranita T, Kohut SJ, Soto PL, Tanda G, Kopajtic TA, Katz JL. Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats. J Pharmacol Exp Ther. 2014 Jan;348(1):174-91. doi: 10.1124/jpet.113.208264. Epub 2013 Nov 5. PubMed PMID: 24194527; PubMed Central PMCID: PMC3868882. 3. Li SM, Kopajtic TA, O'Callaghan MJ, Agoston GE, Cao J, Newman AH, Katz JL. N-substituted benztropine analogs: selective dopamine transporter ligands with a fast onset of action and minimal cocaine-like behavioral effects. J Pharmacol Exp Ther. 2011 Feb;336(2):575-85. doi: 10.1124/jpet.110.173260. Epub 2010 Nov 18. PubMed PMID: 21088247; PubMed Central PMCID: PMC3033723. 4. Asha SE, Kerr A, Jones K, McAlpine A. Benztropine for the relief of acute non-traumatic neck pain (wry neck): a randomised trial. Emerg Med J. 2015 Aug;32(8):616-9. doi: 10.1136/emermed-2014-204317. Epub 2014 Nov 20. PubMed PMID: 25414475.