BMH-23

TargetMol
Product Code: TAR-T23803
Supplier: TargetMol
CodeSizePrice
TAR-T23803-5mg5mg£850.00
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Quantity:
TAR-T23803-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23803-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.
CAS:
510721-85-4
Formula:
C15H15N3
Molecular Weight:
237.306
Purity:
0.98
SMILES:
Cc1cc(C)c2c(N)c3cccc(C)c3nc2n1

References

1. Peltonen K, Colis L, Liu H, J??maa S, Zhang Z, Af H?llstr?m T, Moore HM, Sirajuddin P, Laiho M. Small molecule BMH-compounds that inhibit RNA polymerase I and cause nucleolar stress. Mol Cancer Ther. 2014 Nov;13(11):2537-46. doi: 10.1158/1535-7163.MCT-14-0256. Epub 2014 Oct 2. PubMed PMID: 25277384; PubMed Central PMCID: PMC4221476.