Btm 1042
| Code | Size | Price |
|---|
| TAR-T23829-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T23829-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T23829-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.
CAS:
72293-40-4
Formula:
C21H27Cl2N3OS
Molecular Weight:
440.43
Purity:
0.98
SMILES:
Cl.Cl.CN1CCN(C[C@H]2[C@H](Sc3ccccc3NC2=O)c2ccccc2)CC1
References
1. Noronha-Blob L, Sturm BL, Lowe VC, Jackson KN, Kachur JF. In vitro and in vivo antimuscarinic effects of (-)cis 2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5 benzothiazepin-4-(5H)one HCl (BTM-1086) in guinea pig peripheral tissues. Life Sci. 1990;46(17):1223-31. PubMed PMID: 2338887.
2. Takayanagi I, Nakazo K, Kizawa Y. Possible mechanisms of a new type of antispasmodic drug, BTM-1042(cis-(--)-2,3-dihydro-3-(4-methyl-piperazinyl)methyl-2-phenyl-1,5-benzoth iazepin-4(5H)-one dihydrochloride). Jpn J Pharmacol. 1980 Oct;30(5):647-54. PubMed PMID: 7206371.
3. Yamamoto H, Nakamura Y, Nagasaka M, Asai H. Specificity in the pharmacological actions of optical isomers of cis-2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5- benzothiazepin-4(5H)-one (BTM). Chem Pharm Bull (Tokyo). 1987 Aug;35(8):3419-24. PubMed PMID: 3427721.
4. Asano T, Okumura T, Hirano K, Adachi T, Sugiura M. Competitive enzyme immunoassay for anti-ulcer agent, (-)-cis-2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5- benzothiazepin-4(5H)-one hydrochloride (BTM-1086). Chem Pharm Bull (Tokyo). 1986 Oct;34(10):4238-43. PubMed PMID: 3549012.