CFM-1
| Code | Size | Price |
|---|
| TAR-T23875-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T23875-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T23875-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
CFM-1 is an antagonist of the anaphase-promoting complex (APC)-2. It also is a cell cycle and apoptosis regulatory protein (CARP)-1 interaction antagonist.
CAS:
1380448-60-1
Formula:
C12H7BrN2O2S2
Molecular Weight:
355.22
Purity:
0.98
SMILES:
Cc1cc(Br)cc2C(C(=O)Nc12)=C1SC(=S)NC1=O
References
1. Tavares AC, Bocchi EA, Guimar?es GV. Functional Class in Children with Idiopathic Dilated Cardiomyopathy. A pilot Study. Arq Bras Cardiol. 2016 Jun;106(6):502-9. doi: 10.5935/abc.20160066. Epub 2016 May 6. English, Portuguese. PubMed PMID: 27168472; PubMed Central PMCID: PMC4940149.
2. Alafeefy AM, Ashour AE, Prasad O, Sinha L, Pathak S, Alasmari FA, Rishi AK, Abdel-Aziz HA. Development of certain novel N-(2-(2-(2-oxoindolin-3-ylidene)hydrazinecarbonyl)phenyl)-benzamides and 3-(2-oxoindolin-3-ylideneamino)-2-substituted quinazolin-4(3H)-ones as CFM-1 analogs: design, synthesis, QSAR analysis and anticancer activity. Eur J Med Chem. 2015 Mar 6;92:191-201. doi: 10.1016/j.ejmech.2014.12.048. Epub 2014 Dec 27. PubMed PMID: 25555142.
3. Muthu M, Cheriyan VT, Munie S, Levi E, Frank J, Ashour AE, Singh M, Rishi AK. Mechanisms of neuroblastoma cell growth inhibition by CARP-1 functional mimetics. PLoS One. 2014 Jul 17;9(7):e102567. doi: 10.1371/journal.pone.0102567. eCollection 2014. PubMed PMID: 25033461; PubMed Central PMCID: PMC4102511.
4. Khan NA, Raine LB, Drollette ES, Scudder MR, Pontifex MB, Castelli DM, Donovan SM, Evans EM, Hillman CH. Impact of the FITKids physical activity intervention on adiposity in prepubertal children. Pediatrics. 2014 Apr;133(4):e875-83. doi: 10.1542/peds.2013-2246. Epub 2014 Mar 31. PubMed PMID: 24685956; PubMed Central PMCID: PMC3966501.