Chlorasquin
Code | Size | Price |
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TAR-T23883-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23883-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23883-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Chlorasquin is a dihydrofolate reductase inhibitor.
CAS:
18921-73-8
Formula:
C20H19ClN6O5
Molecular Weight:
458.86
Purity:
0.98
SMILES:
Nc1nc(N)c2c(Cl)c(CNc3ccc(cc3)C(=O)N[C@@H](CC(O)=O)C(O)=O)ccc2n1
References
1. Hynes JB, Eason DE, Garrett CM, Colvin PL Jr. Quinazolines as inhibitors of dihydrofolate reductase. 4. Classical analogues of folic and isofolic acids. J Med Chem. 1977 Apr;20(4):588-91. PubMed PMID: 850245.
2. Chello PL, McQueen CA, DeAngelis LM, Bertino JR. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists. Cancer Res. 1976 Jul;36(7 PT 1):2442-9. PubMed PMID: 1277151.