CJB-090 2HCl
| Code | Size | Price |
|---|
| TAR-T23891-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T23891-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T23891-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
CJB-090 2HCl is a partial agonist of the dopamine D3 receptor.
CAS:
595584-40-0
Formula:
C26H30Cl4N4O
Molecular Weight:
556.35
Purity:
0.98
SMILES:
Cl.Cl.Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(cc3)-c3ccccn3)CC2)c1Cl
References
1. Blaylock BL, Gould RW, Banala A, Grundt P, Luedtke RR, Newman AH, Nader MA. Influence of cocaine history on the behavioral effects of Dopamine D(3) receptor-selective compounds in monkeys. Neuropsychopharmacology. 2011 Apr;36(5):1104-13. doi: 10.1038/npp.2010.248. Epub 2011 Feb 2. Erratum in: Neuropsychopharmacology. 2012 Oct;37(11):2550. PubMed PMID: 21289600; PubMed Central PMCID: PMC3070922.
2. Orio L, Wee S, Newman AH, Pulvirenti L, Koob GF. The dopamine D3 receptor partial agonist CJB090 and antagonist PG01037 decrease progressive ratio responding for methamphetamine in rats with extended-access. Addict Biol. 2010 Jul;15(3):312-23. doi: 10.1111/j.1369-1600.2010.00211.x. Epub 2010 Apr 29. PubMed PMID: 20456290; PubMed Central PMCID: PMC2903631.
3. Mason CW, Hassan HE, Kim KP, Cao J, Eddington ND, Newman AH, Voulalas PJ. Characterization of the transport, metabolism, and pharmacokinetics of the dopamine D3 receptor-selective fluorenyl- and 2-pyridylphenyl amides developed for treatment of psychostimulant abuse. J Pharmacol Exp Ther. 2010 Jun;333(3):854-64. doi: 10.1124/jpet.109.165084. Epub 2010 Mar 12. PubMed PMID: 20228156; PubMed Central PMCID: PMC2879935.
4. Achat-Mendes C, Platt DM, Newman AH, Spealman RD. The dopamine D3 receptor partial agonist CJB 090 inhibits the discriminative stimulus but not the reinforcing or priming effects of cocaine in squirrel monkeys. Psychopharmacology (Berl). 2009 Sep;206(1):73-84. doi: 10.1007/s00213-009-1581-9. Epub 2009 Jun 10. PubMed PMID: 19513698; PubMed Central PMCID: PMC2753862.