Dacopafant
| Code | Size | Price |
|---|
| TAR-T23951-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T23951-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T23951-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Dacopafant is an antagonist of platlet activationg factor receptor.
CAS:
125372-33-0
Formula:
C12H11N3OS
Molecular Weight:
245.3
Purity:
0.98
SMILES:
NC(=O)c1ccn2[C@H](SCc12)c1cccnc1
References
1. Serradji N, Bensaid O, Martin M, Kan E, Dereuddre-Bosquet N, Redeuilh C, Huet J, Heymans F, Lamouri A, Clayette P, Dong CZ, Dormont D, Godfroid JJ. Structure-activity relationships in platelet-activating factor (PAF). 10. From PAF antagonism to inhibition of HIV-1 replication. J Med Chem. 2000 Jun 1;43(11):2149-54. PubMed PMID: 10841793.
2. Clayette P, Dereuddre-Bosquet N, Martin M, Fretier P, Dormont D. Effects of RP 55778, a tumor necrosis factor alpha synthesis inhibitor, on antiviral activity of dideoxynucleosides. Antimicrob Agents Chemother. 1997 Apr;41(4):875-7. PubMed PMID: 9087512; PubMed Central PMCID: PMC163817.
3. Renesto P, Vicart P, Paulin D, Chignard M. Protective effect of platelet activating factor antagonists on cultured endothelial cell lysis induced by elastase or activated neutrophils. Br J Pharmacol. 1996 Mar;117(5):902-6. PubMed PMID: 8851508; PubMed Central PMCID: PMC1909414.
4. van Rossem K, Vermari?n H, Decuyper K, Bourgain R. The role of PAF and the effect of a specific PAF antagonist on local tissue PO2 and neuronal integrity during and after photothrombotic brain infarction in unanesthetised rabbits. Adv Exp Med Biol. 1996;388:423-9. PubMed PMID: 8798843.