TargetMol

Dactylocycline A

Product Code:
 
TAR-T23956
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T23956-5mg5mg£850.00
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Further Information

Bioactivity:
Dactylocyclines A is novel tetracycline derivatives produced by a Dactylosporangium sp. A screen for antibiotics with activity against tetracycline-resistant microorganisms has led to the isolation of Dactylosporangium sp.
CAS:
125622-12-0
Formula:
C31H40ClN3O13
Molecular Weight:
698.12
Purity:
0.98
SMILES:
COC1C(C)OC(CC1(C)NO)OC1(C)C2CC3(O)C(N(C)C)C(O)=C(C(N)=O)C(=O)C3(O)C(O)=C2C(=O)c2c(O)cc(OC)c(Cl)c12

References

1. Wang P, Kim W, Pickens LB, Gao X, Tang Y. Heterologous expression and manipulation of three tetracycline biosynthetic pathways. Angew Chem Int Ed Engl. 2012 Oct 29;51(44):11136-40. doi: 10.1002/anie.201205426. Epub 2012 Sep 28. PubMed PMID: 23024027; PubMed Central PMCID: PMC4070387. 2. Devasthale PV, Mitscher LA, Telikepalli H, Vander Velde D, Zou JY, Ax HA, Tymiak AA. Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. III. Absolute stereochemistry of the dactylocyclines. J Antibiot (Tokyo). 1992 Dec;45(12):1907-13. PubMed PMID: 1490882. 3. Wells JS, O'Sullivan J, Aklonis C, Ax HA, Tymiak AA, Kirsch DR, Trejo WH, Principe P. Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. I. Taxonomy, production, isolation and biological activity. J Antibiot (Tokyo). 1992 Dec;45(12):1892-8. PubMed PMID: 1490880. 4. Tymiak AA, Ax HA, Bolgar MS, Kahle AD, Porubcan MA, Andersen NH. Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. II. Structure elucidation. J Antibiot (Tokyo). 1992 Dec;45(12):1899-906. PubMed PMID: 1490881.