DAT 582
Code | Size | Price |
---|
TAR-T23965-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23965-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23965-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
DAT 582 is a novel serotonin3 receptor antagonist. It is also an effective and long-lasting antiemetic agent
CAS:
141034-42-6
Formula:
C22H29Cl2N5O
Molecular Weight:
450.41
Purity:
0.98
SMILES:
O=C(C1=NNC2=C1C=CC=C2)N[C@H]3CN(CC4=CC=CC(C)=C4)CCN(C)C3.[H]Cl.[H]Cl
References
1. Meyer O, Hoffmann T, Aslan T, Ahrens N, Kiesewetter H, Salama A. Diclofenac-induced antibodies against RBCs and platelets: two case reports and a concise review. Transfusion. 2003 Mar;43(3):345-9. Review. PubMed PMID: 12675720.
2. Kato S, Fujiwara I, Yoshida N. Nitrogen-containing heteroalicycles with serotonin receptor binding affinity: development of gastroprokinetic and antiemetic agents. Med Res Rev. 1999 Jan;19(1):25-73. Review. PubMed PMID: 9918193.
3. Newberry NR, Sprosen TS, Watkins CJ, Leslie RA, Grahame-Smith DG. AS-5370 potently antagonizes 5-HT3 receptor-mediated responses on NG108-15 cells and on the rat vagus. Eur J Pharmacol. 1992 Aug 14;219(1):135-40. PubMed PMID: 1397040.
4. Yoshida N, Omoya H, Kato S, Ito T. 5-HT3 receptor antagonist effects of DAT-582, (R) enantiomer of AS-5370. Eur J Pharmacol. 1992 Jun 17;216(3):435-40. PubMed PMID: 1425931.