DMP 323

TargetMol
Product Code: TAR-T24008
Supplier: TargetMol
CodeSizePrice
TAR-T24008-5mg5mg£1,010.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24008-50mg50mg£1,982.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24008-100mg100mg£2,560.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
DMP 323 is a potent inhibitor of HIV-1 protease.
CAS:
151867-81-1
Formula:
C35H38N2O5
Molecular Weight:
566.698
Purity:
0.98
SMILES:
OCc1ccc(CN2[C@@H](Cc3ccccc3)[C@@H](O)[C@H](O)[C@H](Cc3ccccc3)N(Cc3ccc(CO)cc3)C2=O)cc1

References

1. Singh N, Frushicheva MP, Warshel A. Validating the vitality strategy for fighting drug resistance. Proteins. 2012 Apr;80(4):1110-22. doi: 10.1002/prot.24012. Epub 2012 Jan 31. PubMed PMID: 22275047; PubMed Central PMCID: PMC3299486. 2. Ishikita H, Warshel A. Predicting drug-resistant mutations of HIV protease. Angew Chem Int Ed Engl. 2008;47(4):697-700. PubMed PMID: 18058968. 3. Vilar S, Villaverde MC, Sussman F. Inhibitor docking screened by the modified SAFE_p scoring function: application to cyclic urea HIV-1 PR inhibitors. J Comput Chem. 2007 Oct;28(13):2216-25. PubMed PMID: 17450567. 4. Richter M, Gy?m?nt N, Moln?r J, Hilgeroth A. P-glycoprotein effects of cyclic urea HIV protease inhibitor DMP 323 in competitional absorption studies. Arch Pharm (Weinheim). 2006 Nov;339(11):625-8. PubMed PMID: 17048292.