DMP 323
Code | Size | Price |
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TAR-T24008-5mg | 5mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24008-50mg | 50mg | £1,982.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24008-100mg | 100mg | £2,560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
DMP 323 is a potent inhibitor of HIV-1 protease.
CAS:
151867-81-1
Formula:
C35H38N2O5
Molecular Weight:
566.698
Purity:
0.98
SMILES:
OCc1ccc(CN2[C@@H](Cc3ccccc3)[C@@H](O)[C@H](O)[C@H](Cc3ccccc3)N(Cc3ccc(CO)cc3)C2=O)cc1
References
1. Singh N, Frushicheva MP, Warshel A. Validating the vitality strategy for fighting drug resistance. Proteins. 2012 Apr;80(4):1110-22. doi: 10.1002/prot.24012. Epub 2012 Jan 31. PubMed PMID: 22275047; PubMed Central PMCID: PMC3299486.
2. Ishikita H, Warshel A. Predicting drug-resistant mutations of HIV protease. Angew Chem Int Ed Engl. 2008;47(4):697-700. PubMed PMID: 18058968.
3. Vilar S, Villaverde MC, Sussman F. Inhibitor docking screened by the modified SAFE_p scoring function: application to cyclic urea HIV-1 PR inhibitors. J Comput Chem. 2007 Oct;28(13):2216-25. PubMed PMID: 17450567.
4. Richter M, Gy?m?nt N, Moln?r J, Hilgeroth A. P-glycoprotein effects of cyclic urea HIV protease inhibitor DMP 323 in competitional absorption studies. Arch Pharm (Weinheim). 2006 Nov;339(11):625-8. PubMed PMID: 17048292.