DNDI-8219
Code | Size | Price |
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TAR-T24011-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.
CAS:
1333170-15-2
Formula:
C13H10F3N3O5
Molecular Weight:
345.234
Purity:
0.98
SMILES:
[O-][N+](=O)c1cn2C[C@H](COc2n1)Oc1ccc(OC(F)(F)F)cc1
References
1. Thompson AM, O'Connor PD, Marshall AJ, Blaser A, Yardley V, Maes L, Gupta S, Launay D, Braillard S, Chatelain E, Wan B, Franzblau SG, Ma Z, Cooper CB, Denny WA. Development of (6R)-2-nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (DNDI-8219): a new lead for visceral leishmaniasis. J Med Chem. 2018 Feb 20. doi: 10.1021/acs.jmedchem.7b01581. [Epub ahead of print] PubMed PMID: 29461823.