DS-5272
Code | Size | Price |
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TAR-T24019-5mg | 5mg | £2,456.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24019-50mg | 50mg | £4,874.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24019-100mg | 100mg | £6,898.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
DS-5272 is a potent and orally active inhibitor of p53-MDM2 interaction.
CAS:
1235575-97-9
Formula:
C34H38Cl2F2N6O2S
Molecular Weight:
703.67
Purity:
0.98
SMILES:
CC[C@@H]1CNC2(CC2)CN1C(=O)[C@@H]1C[C@@H](F)CN1C(=O)C1=C(C(C)C)N2[C@H](c3ccc(Cl)c(F)c3)[C@@](C)(N=C2S1)c1ccc(Cl)nc1
References
1. Miyazaki M, Uoto K, Sugimoto Y, Naito H, Yoshida K, Okayama T, Kawato H, Miyazaki M, Kitagawa M, Seki T, Fukutake S, Aonuma M, Soga T. Discovery of DS-5272 as a promising candidate: A potent and orally active p53-MDM2 interaction inhibitor. Bioorg Med Chem. 2015 May 15;23(10):2360-7. doi: 10.1016/j.bmc.2015.03.069. Epub 2015 Mar 31. PubMed PMID: 25882531.