Fibrostatin C
| Code | Size | Price |
|---|
| TAR-T24062-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Fibrostatin C is an inhibitor of prolyl 4-hydroxylase. It is produced by Streptomyces catenulae subsp.
CAS:
91776-47-5
Formula:
C18H19NO8S
Molecular Weight:
409.41
Purity:
0.98
SMILES:
COC1=CC(=O)c2c(O)c(CSC[C@H](NC(C)=O)C(O)=O)c(OC)cc2C1=O
References
1. Saika S, Ooshima A, Yamanaka O, Okada Y, Tanaka S, Ohnishi Y. Effect of fibrostatin C, an inhibitor of prolyl 4-hydroxylase, on collagen secretion by human Tenon's capsule fibroblasts in vitro. Graefes Arch Clin Exp Ophthalmol. 1996 Aug;234 Suppl 1:S214-22. PubMed PMID: 8871177.
2. Kawaguchi Y, Harigai M, Kitani A, Suzuki K, Kawakami M, Ishizuka T, Hidaka T, Hara M, Kawagoe M, Nakamura H. Effect of prolyl 4-hydroxylase inhibitor on fibroblast collagen production in vitro: an approach to the treatment of systemic sclerosis. J Rheumatol. 1992 Nov;19(11):1710-5. PubMed PMID: 1337110.
3. Ishimaru T, Kanamaru T, Takahashi T, Okazaki H. Inhibition of prolyl hydroxylase activity and collagen biosynthesis by fibrostatin C, a novel inhibitor produced by Streptomyces catenulae subsp. griseospora No. 23924. J Antibiot (Tokyo). 1988 Nov;41(11):1668-74. PubMed PMID: 2848793.
4. Ohta K, Kasahara F, Ishimaru T, Wada Y, Kanamaru T, Okazaki H. Structures of fibrostatins, new inhibitors of prolyl hydroxylase. J Antibiot (Tokyo). 1987 Sep;40(9):1239-48. PubMed PMID: 2824420.