GP17
| Code | Size | Price |
|---|
| TAR-T24098-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24098-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24098-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
GP17 is a type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.
CAS:
1415050-57-5
Formula:
C26H21F3N4O
Molecular Weight:
462.476
Purity:
0.98
SMILES:
Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1ccc2nc(NC3CC3)ncc2c1
References
1. Mehla J, Dedrick RM, Caufield JH, Wagemans J, Sakhawalkar N, Johnson A, Hatfull GF, Uetz P. Virus-host protein-protein interactions of mycobacteriophage Giles. Sci Rep. 2017 Nov 28;7(1):16514. doi: 10.1038/s41598-017-16303-7. PubMed PMID: 29184079; PubMed Central PMCID: PMC5705681.
2. Lin S, Alam TI, Kottadiel VI, VanGessel CJ, Tang WC, Chemla YR, Rao VB. Altering the speed of a DNA packaging motor from bacteriophage T4. Nucleic Acids Res. 2017 Nov 2;45(19):11437-11448. doi: 10.1093/nar/gkx809. PubMed PMID: 28981683; PubMed Central PMCID: PMC5737356.
3. Zinke M, Fricke P, Samson C, Hwang S, Wall JS, Lange S, Zinn-Justin S, Lange A. Bacteriophage Tail-Tube Assembly Studied by Proton-Detected 4D Solid-State NMR. Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9497-9501. doi: 10.1002/anie.201706060. Epub 2017 Jul 7. PubMed PMID: 28644511; PubMed Central PMCID: PMC5582604.
4. Wang L, Li J, Yang F, E Y, Raza W, Huang Q, Shen Q. Application of Bioorganic Fertilizer Significantly Increased Apple Yields and Shaped Bacterial Community Structure in Orchard Soil. Microb Ecol. 2017 Feb;73(2):404-416. doi: 10.1007/s00248-016-0849-y. Epub 2016 Sep 26. PubMed PMID: 27670433.