TargetMol

HEC72702

Product Code:
 
TAR-T24135
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24135-5mg5mg£1,091.00
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TAR-T24135-50mg50mg£2,143.00
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Quantity:
TAR-T24135-100mg100mg£2,801.00
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This product comes from: United States.
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Further Information

Bioactivity:
HEC72702 is a novel Hepatitis B virus capsid inhibitor, based on clinical candidate GLS4. HEC72702 was found to display no induction of the CYP1A2, CYP3A4, or CYP2B6 enzyme at the high concentration of 10 μM.
CAS:
1793063-59-8
Formula:
C24H26BrFN4O5S
Molecular Weight:
581.46
Purity:
0.98
SMILES:
CCOC(=O)C1=C(CN2CCO[C@H](CCC(O)=O)C2)NC(=N[C@H]1c1ccc(F)cc1Br)c1nccs1

References

1. Ren Q, Liu X, Yan G, Nie B, Zou Z, Li J, Chen Y, Wei Y, Huang J, Luo Z, Gu B, Goldmann S, Zhang J, Zhang Y. 3-((R)-4-(((R)-6-(2-Bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)propanoic Acid (HEC72702), a Novel Hepatitis B Virus Capsid Inhibitor Based on Clinical Candidate GLS4. J Med Chem. 2018 Jan 30. doi: 10.1021/acs.jmedchem.7b01914. [Epub ahead of print] PubMed PMID: 29381358.