Hns 32
| Code | Size | Price |
|---|
| TAR-T24145-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Hns 32 possesses antiarrhythmic properties in dog and guinea pig hearts. It also has vasodilator action.
CAS:
186086-10-2
Formula:
C26H33N3
Molecular Weight:
387.571
Purity:
0.98
SMILES:
CC(C)c1ccc(C)c2c(C(=N/Cc3ccccn3)N(C)C)c(C)c(C)c2c1C
References
1. Saitoh M, Sugiyama A, Nakazawa T, Hashimoto K. Cardiovascular effects of orally administered HNS-32, an originally synthesized azulene-1-carboxamidine derivative, assessed in the in vivo rat model. Jpn J Pharmacol. 2002 Jul;89(3):316-9. PubMed PMID: 12184739.
2. Tanaka Y, Shigenobu K. A review of HNS-32: a novel azulene-1-carboxamidine derivative with multiple cardiovascular protective actions. Cardiovasc Drug Rev. 2001 Winter;19(4):297-312. Review. PubMed PMID: 11830749.
3. Noguchi K, Kase J, Saitoh M, Masumiya H, Saitoh M, Nakazawa T, Tanaka Y, Tanaka H, Hashimoto K, Shigenobu K. Effects of HNS-32, a novel antiarrhythmic agent, on guinea-pig myocardium. Pharmacology. 2002 Jan;64(1):36-42. PubMed PMID: 11731720.
4. Noguchi K, Saitoh M, Nakazawa T, Tanaka H, Tanaka Y, Shigenobu K. Cerebral artery selective inhibition of protein kinase c-mediated contraction by hns-32, a novel azulene-1-carboxamidine derivative. Res Commun Mol Pathol Pharmacol. 2000;107(1-2):45-54. PubMed PMID: 11334370.