BIX02189

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TargetMol
Product Code: TAR-T2416
Supplier: TargetMol
CodeSizePrice
TAR-T2416-1mg1mg£98.00
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TAR-T2416-2mg2mg£109.00
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TAR-T2416-5mg5mg£134.00
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TAR-T2416-1mL1 mL * 10 mM (in DMSO)£141.00
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TAR-T2416-10mg10mg£171.00
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TAR-T2416-25mg25mg£258.00
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TAR-T2416-50mg50mg£389.00
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TAR-T2416-100mg100mg£619.00
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TAR-T2416-200mg200mg£835.00
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TAR-T2416-500mg500mg£1,187.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM.
CAS:
1094614-85-3
Formula:
C27H28N4O2
Molecular Weight:
440.54
Pathway:
Stem Cells; MAPK
Purity:
0.9986
SMILES:
CN(Cc1cc(NC(c2ccccc2)=C3C(Nc4c3ccc(C(N(C)C)=O)c4)=O)ccc1)C
Target:
ERK; MEK; TGF-beta/Smad

References

1. Tatake RJ, et al. Biochem Biophys Res Commun, 2008, 377(1), 120-125. 2. Lim JH, et al. Anat Cell Biol, 2011, 44(4), 265-273. 3. Kimura TE, et al. Circ Res, 2010, 106(5), 961-970.