IMM-H004
| Code | Size | Price |
|---|
| TAR-T24161-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24161-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24161-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
IMM-H004 is an effective inhibitor of BV2 microglia activation.
CAS:
1456807-80-9
Formula:
C16H20N2O4
Molecular Weight:
304.346
Purity:
0.98
SMILES:
COc1cc(O)cc2oc(=O)c(N3CCN(C)CC3)c(C)c12
References
1. Jiang J, Zhang Z, Zou X, Wang R, Bai J, Zhao S, Fan X, Sheng L, Li Y. Determination of IMM-H004 and its active glucuronide metabolite in rat plasma and Ringer's solution by ultra-performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Feb 1;1074-1075:16-24. doi: 10.1016/j.jchromb.2017.12.030. Epub 2017 Dec 29. PubMed PMID: 29329091.
2. Knecht T, Story J, Liu J, Davis W, Borlongan CV, Dela Pe?a IC. Adjunctive Therapy Approaches for Ischemic Stroke: Innovations to Expand Time Window of Treatment. Int J Mol Sci. 2017 Dec 19;18(12). pii: E2756. doi: 10.3390/ijms18122756. Review. PubMed PMID: 29257093; PubMed Central PMCID: PMC5751355.
3. Niu F, Song XY, Hu JF, Zuo W, Kong LL, Wang XF, Han N, Chen NH. IMM-H004, A New Coumarin Derivative, Improved Focal Cerebral Ischemia via Blood-Brain Barrier Protection in Rats. J Stroke Cerebrovasc Dis. 2017 Oct;26(10):2065-2073. doi: 10.1016/j.jstrokecerebrovasdis.2016.11.121. Epub 2017 Jun 29. PubMed PMID: 28669655.
4. Zhang Z, Wu X, Zhao M, Yang Y, Wang Y, Hu J, Wang B, Sheng L, Li Y. Determination of IMM-H004, a novel neuroprotective agent, in rat plasma and brain tissue by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 24;1048:49-55. doi: 10.1016/j.jchromb.2017.02.005. Epub 2017 Feb 6. PubMed PMID: 28213295.