Jatrophone
| Code | Size | Price |
|---|
| TAR-T24195-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Jatrophone is a novel inhibitor of the macrocyclic diterpenoid tumor.
CAS:
29444-03-9
Formula:
C20H24O3
Molecular Weight:
312.409
Purity:
0.98
SMILES:
C[C@@H]1C[C@@]23OC(CC(C)(C)C=C/C(=O)/C(C)=CC2=C1)=C(C)C3=O
References
1. Fatima I, El-Ayachi I, Taotao L, Angeles Lillo M, Krutilina RI, Seagroves TN, Radaszkiewicz TW, Hutnan M, Bryja V, Krum SA, Rivas F, Miranda-Carboni GA. Correction: The natural compound Jatrophone interferes with Wnt/?-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer. PLoS One. 2018 May 17;13(5):e0197796. doi: 10.1371/journal.pone.0197796. eCollection 2018. PubMed PMID: 29771986.
2. Zolezzi JM, Lindsay CB, Serrano FG, Ureta RC, Theoduloz C, Schmeda-Hirschmann G, Inestrosa NC. Neuroprotective Effects of Ferruginol, Jatrophone, and Junicedric Acid Against Amyloid-? Injury in Hippocampal Neurons. J Alzheimers Dis. 2018;63(2):705-723. doi: 10.3233/JAD-170701. PubMed PMID: 29660932.
3. Fatima I, El-Ayachi I, Taotao L, Lillo MA, Krutilina R, Seagroves TN, Radaszkiewicz TW, Hutnan M, Bryja V, Krum SA, Rivas F, Miranda-Carboni GA. The natural compound Jatrophone interferes with Wnt/?-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer. PLoS One. 2017 Dec 27;12(12):e0189864. doi: 10.1371/journal.pone.0189864. eCollection 2017. Erratum in: PLoS One. 2018 May 17;13(5):e0197796. PubMed PMID: 29281678; PubMed Central PMCID: PMC5744972.
4. Fr?hlich JK, Stein T, da Silva LA, Biavatti MW, Tonussi CR, Lemos-Senna E. Antinociceptive and anti-inflammatory activities of the Jatropha isabellei dichloromethane fraction and isolation and quantitative determination of jatrophone by UFLC-DAD. Pharm Biol. 2017 Dec;55(1):1215-1222. doi: 10.1080/13880209.2017.1295999. PubMed PMID: 28249559.