PHT-427

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TargetMol
Product Code: TAR-T2420
Supplier: TargetMol
CodeSizePrice
TAR-T2420-10mg10mg£102.00
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Quantity:
TAR-T2420-1mL1 mL * 10 mM (in DMSO)£105.00
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Quantity:
TAR-T2420-25mg25mg£134.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2420-50mg50mg£195.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2420-100mg100mg£282.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2420-200mg200mg£434.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
PHT-427 is a dual Akt (Ki: 2.7 μM) and PDPK1 (Ki: 5.2 μM) inhibitor (high-affinity binding for the PH domains of Akt and PDPK1).
CAS:
1191951-57-1
Formula:
C20H31N3O2S2
Molecular Weight:
409.61
Pathway:
Cytoskeletal Signaling; Apoptosis; PI3K/Akt/mTOR signaling
Purity:
0.9977
SMILES:
CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Target:
Apoptosis; Akt; PDK

References

1. Meuillet EJ, et al. Mol Cancer Ther, 2010, 9(3), 706-717. 2. Moses SA, et al. Cancer Res, 2009, 69(12), 5073-5081.