L 158809
| Code | Size | Price |
|---|
| TAR-T24282-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24282-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24282-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
L 158809 is an antagonist of the angiotensin II type 1 receptor.
CAS:
133240-46-7
Formula:
C24H23N7
Molecular Weight:
409.497
Purity:
0.98
SMILES:
CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1
References
1. Saez F, Reverte V, Paliege A, Moreno JM, Llin?s MT, Bachmann S, Salazar FJ. Sex-dependent hypertension and renal changes in aged rats with altered renal development. Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F461-70. doi: 10.1152/ajprenal.00198.2014. Epub 2014 Jun 18. PubMed PMID: 24944267.
2. Kitada K, Yui N, Mori T, Ohkita M, Matsumura Y. Vasoprotective effects of an endothelin receptor antagonist in ovariectomized female rats. Life Sci. 2014 Nov 24;118(2):379-85. doi: 10.1016/j.lfs.2014.01.009. Epub 2014 Jan 24. PubMed PMID: 24468711.
3. Moore ED, Kooshki M, Wheeler KT, Metheny-Barlow LJ, Robbins ME. Differential expression of Homer1a in the hippocampus and cortex likely plays a role in radiation-induced brain injury. Radiat Res. 2014 Jan;181(1):21-32. doi: 10.1667/RR13475.1. Epub 2013 Dec 30. PubMed PMID: 24377717; PubMed Central PMCID: PMC4118588.
4. Meinen S, Lin S, Ruegg MA. Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-?2-deficient congenital muscular dystrophy (MDC1A). Skelet Muscle. 2012 Sep 3;2(1):18. doi: 10.1186/2044-5040-2-18. PubMed PMID: 22943509; PubMed Central PMCID: PMC3598380.