L 658758
Code | Size | Price |
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TAR-T24311-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24311-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24311-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
L 658758 is an inhibitor of serine proteinase.
CAS:
116507-04-1
Formula:
C16H20N2O9S
Molecular Weight:
416.4
Purity:
0.98
SMILES:
[H][C@@]12[C@@H](OC)C(=O)N1C(C(=O)N1CCC[C@H]1C(O)=O)=C(COC(C)=O)CS2(=O)=O
References
1. Kawai M, Harada N, Takeyama H, Okajima K. Neutrophil elastase contributes to the development of ischemia/reperfusion-induced liver injury by decreasing the production of insulin-like growth factor-I in rats. Transl Res. 2010 Jun;155(6):294-304. doi: 10.1016/j.trsl.2010.02.003. Epub 2010 Mar 19. PubMed PMID: 20478544.
2. Harada N, Okajima K, Isobe H. Role of neutrophil elastase in development of pulmonary vascular injury and septic shock in rats. Shock. 2008 Oct;30(4):379-87. doi: 10.1097/SHK.0b013e3181673e2c. Erratum in: Shock. 2012 Oct;38(4):446. PubMed PMID: 18323746.
3. Okajima K, Harada N, Uchiba M, Mori M. Neutrophil elastase contributes to the development of ischemia-reperfusion-induced liver injury by decreasing endothelial production of prostacyclin in rats. Am J Physiol Gastrointest Liver Physiol. 2004 Dec;287(6):G1116-23. Epub 2004 Jul 8. PubMed PMID: 15246960.
4. Liu W, Okajima K, Murakami K, Harada N, Isobe H, Irie T. Role of neutrophil elastase in stress-induced gastric mucosal injury in rats. J Lab Clin Med. 1998 Nov;132(5):432-9. PubMed PMID: 9823937.