L 668169
| Code | Size | Price |
|---|
| TAR-T24319-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
L 668169 is a tachykinin antagonist.
CAS:
137012-28-3
Formula:
C82H108N16O14S2
Molecular Weight:
1605.98
Purity:
0.98
SMILES:
CSCCC1NC(=O)C(CC(C)C)N2CCC(NC(=O)C(Cc3ccccc3)N(C)C(=O)C(Cc3c[nH]c4ccccc34)NC(=O)C(CCC(N)=O)NC(=O)C(CCSC)NC(=O)C(CC(C)C)N3CCC(NC(=O)C(Cc4ccccc4)N(C)C(=O)C(Cc4c[nH]c5ccccc45)NC(=O)C(CCC(N)=O)NC1=O)C3=O)C2=O
References
1. Tao YX, Zhao ZQ. [Neurokinin-1 receptor mediated formalin-induced c-fos expression in the rat spinal cord]. Sheng Li Xue Bao. 1998 Aug;50(4):361-6. Chinese. PubMed PMID: 11324543.
2. Tao YX, Wei F, Zhao ZQ. A contribution of neurokinin-1 receptor to formalin-induced c-fos expression in the rat spinal dorsal horn. Neurosci Lett. 1997 Jan 17;221(2-3):105-8. PubMed PMID: 9121675.
3. Lebrun CJ, Wende P, Steckelings U, Itoi K, Unger T. Effects of tachykinins on phosphoinositide metabolism in the hypothalamus: is the NK1 receptor involved? Brain Res. 1993 Dec 31;632(1-2):74-9. PubMed PMID: 7511982.
4. Seabrook GR, Main MJ, Razzaque Z, Longmore J. Differences in the effects of tachykinin NK1 receptor antagonists: neuronal versus smooth muscle tissues. Eur J Pharmacol. 1993 Nov 30;250(1):125-31. PubMed PMID: 7509748.