L 669083
| Code | Size | Price |
|---|
| TAR-T24322-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24322-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24322-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
L 669083 is two classes of potent leukotriene biosynthesis inhibitors photoaffinity analogue.
CAS:
130007-52-2
Formula:
C29H29IN4O5S
Molecular Weight:
672.54
Purity:
0.98
SMILES:
CC(C)c1ccc2n(Cc3ccc(O)c(I)c3)c(CC(C)(C)C(O)=O)c(c2c1)S(=O)(=O)c1ccc(cc1)N=[N+]=[N-]
References
1. Vickers PJ, Adam M, Charleson S, Coppolino MG, Evans JF, Mancini JA. Identification of amino acid residues of 5-lipoxygenase-activating protein essential for the binding of leukotriene biosynthesis inhibitors. Mol Pharmacol. 1992 Jul;42(1):94-102. PubMed PMID: 1635556.
2. Mancini JA, Prasit P, Coppolino MG, Charleson P, Leger S, Evans JF, Gillard JW, Vickers PJ. 5-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors. Mol Pharmacol. 1992 Feb;41(2):267-72. PubMed PMID: 1538707.
3. Reid GK, Kargman S, Vickers PJ, Mancini JA, L?veill? C, Ethier D, Miller DK, Gillard JW, Dixon RA, Evans JF. Correlation between expression of 5-lipoxygenase-activating protein, 5-lipoxygenase, and cellular leukotriene synthesis. J Biol Chem. 1990 Nov 15;265(32):19818-23. PubMed PMID: 2174053.
4. Miller DK, Gillard JW, Vickers PJ, Sadowski S, L?veill? C, Mancini JA, Charleson P, Dixon RA, Ford-Hutchinson AW, Fortin R, et al. Identification and isolation of a membrane protein necessary for leukotriene production. Nature. 1990 Jan 18;343(6255):278-81. PubMed PMID: 2300172.