L 670548
Code | Size | Price |
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TAR-T24324-5mg | 5mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24324-50mg | 50mg | £1,982.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24324-100mg | 100mg | £2,560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
L 670548 is an agonist of muscarinic receptor.
CAS:
121564-89-4
Formula:
C9H13N3O
Molecular Weight:
179.223
Purity:
0.98
SMILES:
Cc1noc(n1)C1CN2CCC1C2
References
1. Ellis JL, Harman D, Gonzalez J, Spera ML, Liu R, Shen TY, Wypij DM, Zuo F. Development of muscarinic analgesics derived from epibatidine: role of the M4 receptor subtype. J Pharmacol Exp Ther. 1999 Mar;288(3):1143-50. Erratum in: J Pharmacol Exp Ther 1999 May;289(2):1184. PubMed PMID: 10027852.
2. Freedman SB, Patel S, Harley EA, Iversen LL, Baker R, Showell GA, Saunders J, McKnight A, Newberry N, Scholey K, et al. L-687,306: a functionally selective and potent muscarinic M1 receptor agonist. Eur J Pharmacol. 1992 Apr 29;215(1):135-6. PubMed PMID: 1516645.
3. Showell GA, Baker R, Davis J, Hargreaves R, Freedman SB, Hoogsteen K, Patel S, Snow RJ. Synthesis and in vitro biological profile of all four isomers of the potent muscarinic agonist 3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-azabicyclo[2.2.1]heptane. J Med Chem. 1992 Mar 6;35(5):911-6. PubMed PMID: 1548680.
4. Thompson AK, Fisher SK. Preferential coupling of cell surface muscarinic receptors to phosphoinositide hydrolysis in human neuroblastoma cells. J Biol Chem. 1991 Mar 15;266(8):5004-10. PubMed PMID: 1848233.