TargetMol

L 691831

Product Code:
 
TAR-T24342
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24342-5mg5mg£1,010.00
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TAR-T24342-50mg50mg£1,982.00
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Quantity:
TAR-T24342-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
L 691831 is a radioiodinated leukotriene synthesis inhibitor.
CAS:
136668-70-7
Formula:
C36H38N2O4
Molecular Weight:
562.71
Purity:
0.98
SMILES:
CC(C)(C)CC(=O)c1c(CC(C)(C)C(O)=O)n(Cc2ccccc2)c2ccc(OCc3ccc4ccccc4n3)cc12

References

1. Macdonald D, Brideau C, Chan CC, Falgueyret JP, Frenette R, Guay J, Hutchinson JH, Perrier H, Prasit P, Riendeau D, Tagari P, Th?rien M, Young RN, Girard Y. Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2023-7. doi: 10.1016/j.bmcl.2008.01.105. Epub 2008 Feb 2. PubMed PMID: 18276139. 2. Charleson S, Evans JF, L?ger S, Perrier H, Prasit P, Wang Z, Vickers PJ. Structural requirements for the binding of fatty acids to 5-lipoxygenase-activating protein. Eur J Pharmacol. 1994 May 17;267(3):275-80. PubMed PMID: 8088366. 3. Mancini JA, Coppolino MG, Klassen JH, Charleson S, Vickers PJ. The binding of leukotriene biosynthesis inhibitors to site-directed mutants of human 5-lipoxygenase-activating protein. Life Sci. 1994;54(9):PL137-42. PubMed PMID: 8114608. 4. Mancini JA, Abramovitz M, Cox ME, Wong E, Charleson S, Perrier H, Wang Z, Prasit P, Vickers PJ. 5-lipoxygenase-activating protein is an arachidonate binding protein. FEBS Lett. 1993 Mar 8;318(3):277-81. PubMed PMID: 8440384.