IC261

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TargetMol
Product Code: TAR-T2440
Supplier: TargetMol
CodeSizePrice
TAR-T2440-5mg5mg£122.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T2440-1mL1 mL * 10 mM (in DMSO)£127.00
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Quantity:
TAR-T2440-10mg10mg£149.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2440-25mg25mg£222.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2440-50mg50mg£303.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2440-100mg100mg£414.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2440-500mg500mg£849.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.
CAS:
186611-52-9
Formula:
C18H17NO4
Molecular Weight:
311.337
Pathway:
Metabolism; Cell Cycle/Checkpoint; Apoptosis; Stem Cells
Purity:
0.9986
SMILES:
COc1cc(OC)c(C=C2C(=O)Nc3ccccc23)c(OC)c1
Target:
Apoptosis; Casein Kinase; CDK

References

1. Behrend L, et al. Oncogene. 2000, 19(47):5303-5313. 2. Sakurai E, et al. Mol Pain. 2009, 5:74. 3. Brockschmidt C, et al. Gut. 2008, 57(6):799-806. 4. Liu F, et al. Proc Natl Acad Sci U S A. 2001, 98(20):11062-11068.