MEN 10207
| Code | Size | Price |
|---|
| TAR-T24446-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
MEN 10207 is an antagonist of tachykinin.
CAS:
126050-12-2
Formula:
C57H68N14O10
Molecular Weight:
1109.259
Purity:
0.98
SMILES:
CC(C)[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
References
1. Mussap CJ, Stamatakos C, Burcher E. Radioligand binding, autoradiographic and functional studies demonstrate tachykinin NK-2 receptors in dog urinary bladder. J Pharmacol Exp Ther. 1996 Oct;279(1):423-34. PubMed PMID: 8859022.
2. Burcher E, Zeng XP, Strigas J, Geraghty DP, Lavielle S. Tachykinin receptors in guinea-pig airways: characterization using selective ligands. Can J Physiol Pharmacol. 1995 Jul;73(7):915-22. PubMed PMID: 8846430.
3. Medeiros MD, Turner AJ. Metabolic stability of some tachykinin analogues to cell-surface peptidases: roles for endopeptidase-24.11 and aminopeptidase N. Peptides. 1995;16(3):441-7. PubMed PMID: 7651897.
4. Parrish MB, Rainsford KD, Johnson DM, Daniel EE. NK1 receptors mediated release of 6-keto-PGF1 alpha from the ex vivo perfused canine ileum. J Pharmacol Exp Ther. 1994 Oct;271(1):39-47. PubMed PMID: 7525925.